Alexandra Gimbernat, Hector Osuna and Eric Valery
APPLEXION SAS, 5 chemin du Pilon, 01700 Saint-Maurice de Beynost, France; hector.osuna@applexion.com
Chromatography is a technique of choice for the purification of saccharides (glucose, fructose, sucrose, oligosaccharides). APPLEXION has developed a digital tool (Perform 4.0) to validate the design of an industrial chromatography system from pilot scale and to enhance production and reduce chemicals and energy consumption. Process development comprised experiments at laboratory scale, modeling, simulation and digital tool configuration. Perform 4.0 helped the conduct of an industrial unit by choosing optimal settings and maintaining production.